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How to Use Claude Science: Complete Guide July 2026

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How to Use Claude Science: A Complete Guide

Claude Science, launched by Anthropic on June 30, 2026, is an AI research workbench designed to accelerate scientific discovery. This guide covers everything you need to know to get started — from access to advanced workflows.

Getting Started

Step 1: Check Your Access

Claude Science is available to all paid Claude users:

PlanMonthly PriceAccess
Pro$20Full access
Max 5x$100Full access
Max 20x$200Full access
Team$25/seat/moAdmin must enable
EnterpriseCustomAdmin must enable
Free$0❌ Not available

Step 2: Open Claude Science

  • Go to claude.ai and log in
  • Select “Science” from the mode picker (top of the chat interface)
  • You can also navigate directly to science.claude.ai
  • The interface shows a research-focused workspace with:
    • A chat input for natural-language research requests
    • A code execution panel (Python/R/shell)
    • A visualization area for scientific displays
    • A reference panel showing fetched literature

Step 3: Start a Research Session

Type a research question or task in natural language. Claude Science handles:

  • Literature search: “Search PubMed for recent papers on CRISPR-Cas9 delivery using lipid nanoparticles”
  • Data analysis: “Analyze this single-cell RNA-seq dataset and identify differentially expressed genes”
  • Visualization: “Generate a volcano plot of the differentially expressed genes with log2 fold change > 1”
  • Code execution: “Write and run a Python script to perform PCA on this gene expression matrix”

Core Workflows

Workflow 1: Literature Review with Code Execution

  1. Ask Claude Science to search for recent papers on a topic
  2. It retrieves results from PubMed and scientific databases
  3. Ask it to extract, analyze, or visualize data from the papers
  4. Claude Science writes and executes code to produce the analysis
  5. The reviewer agent checks citations and calculations

Example: “Search for papers on multimodal AI in drug discovery published in 2026. Extract the top 10 compounds mentioned and create a bar chart of their binding affinities.”

Workflow 2: Computational Biology Analysis

Claude Science excels at bioinformatics tasks:

  • Genomics: Align reads, call variants, generate coverage tracks
  • Single-cell: Perform clustering, UMAP projections, marker gene identification
  • Proteomics: Analyze protein structures, visualize PDB files in 3D
  • Cheminformatics: Analyze chemical libraries, predict properties

Example: “Load this single-cell dataset, perform QC filtering, normalize using SCTransform, cluster at resolution 0.8, and generate a UMAP colored by cluster.”

Workflow 3: Reproducible Figure Generation

Every figure includes embedded source code:

  1. Describe the figure you want
  2. Claude Science writes the code (Python/matplotlib, R/ggplot2, etc.)
  3. It executes the code and renders the figure
  4. The figure includes a “Show Code” button with full provenance
  5. Request changes in plain English and Claude Science updates the code

Example: “Create a multi-panel figure showing (A) the expression heatmap of the top 20 genes, (B) a UMAP colored by cell type, and (C) a bar chart of cell type proportions.”

Advanced Features

Upload Your Own Data

  • Supported formats: CSV, TSV, Excel, FCS, FASTA, BAM, CRAM, VCF, PDB, SDF, SMA (SMILES)
  • Drop files directly into the chat or use the file upload button
  • Claude Science reads, parses, and analyzes the data

Use the Reviewer Agent

After generating results, type “Review this analysis” or click the Review button. The reviewer agent checks:

  • Do the cited papers actually support the claims?
  • Do the numbers in the text match the code output?
  • Could the figure have been produced by the attached code?

Export Results

  • Figures: Download as PNG, SVG, or PDF
  • Code: Export the full notebook (Python or R)
  • Report: Generate a complete research summary with all citations

Tips for Best Results

  1. Be specific: “Analyze this scRNA-seq dataset” → better with “Perform QC, normalize, cluster at 0.8 resolution, and generate a UMAP”
  2. Upload your data first: Even for literature searches, uploading your reference data produces better results
  3. Use the reviewer: Always run the reviewer before using results in a paper or presentation
  4. Iterate: Claude Science excels at refinement — “Make the points larger” or “Change the color scheme to viridis”
  5. Compute limits: Large analyses (whole-genome sequencing, large single-cell datasets) may hit compute limits; use cloud VMs for heavy workloads

Limitations

  • Not available on Free tier
  • Computational biology focus: strongest in bioinformatics; weaker in experimental physics or chemistry
  • Compute limits: very large datasets may need cloud VM execution
  • Still beta: Anthropic describes it as “public beta” as of July 2026
  • AI for Science grants: Applications close July 15, 2026 (up to $30,000 in Claude credits)

What You Cannot Do

Claude Science cannot:

  • Control laboratory equipment
  • Perform wet-lab experiments
  • Access paywalled journals (only public databases)
  • Generate unlimited compute (daily rate limits apply)
  • Run very large datasets (>10GB recommended limit)

Sources